I am a research scientist from a multidisciplinary background in physics, applied mathematics, engineering and molecular neuroscience. I have well-developed laboratory and computational modelling skills across these disciplines that are complemented by sound capabilities in qualitative and quantitative analysis. In addition, I am a strong science communicator with expertise in technical and science writing, which has underpinned my ability to work and effectively communicate across different scientific disciplines.
My over-riding research interest is in systems biology, bringing together modelling tools and strengths from my own academic background to help understand the complex mechanisms of Alzheimer’s. I have specific interests in the following factors that I believe may play a role in our genetic susceptibility to developing Alzheimer’s disease.
Hormones: With a disproportionate number of women around the world living with Alzheimer’s, I am interested to explore the unique biological reasons for this difference.
Environmental factors: We are becomingly increasingly exposed to chemicals that are biologically incompatible to our well-being through our food and water supplies, and our physical environment in general. I am interested to understand how this exposure may or may not affect the increasing prevalence of Alzheimer’s in the world today.
Introducing A New Systems Pathology Paradigm of Alzheimer’s Disease. Rollo JL, Crawford J, Zhang X, Hardy, J. Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association. >> Download a copy: http://dx.doi.org/10.1016/j.jalz.2017.06.1927
Unraveling the mechanistic complexity of Alzheimer’s disease through systems biology. Rollo JL et.al. Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association. >> Download a copy: http://dx.doi.org/10.1016/j.jalz.2015.10.010.
Association Rules Analysis of Comorbidity and Multimorbidity: The Concord Health and Aging in Men Project. Held F, Blyth F, Gnjidic D, Hirani V, Naganathan V, Waite L, Seibel M, Rollo J, Handelsman D, Cumming R, Le Couteur D. The Journals of Gerontology Series A Biological Sciences and Medical Sciences. >> Download a copy: http://dx.doi.org/10.1093/gerona/glv181